DPP6 as a candidate gene for neuroleptic-induced tardive dyskinesia

Clozapine-induced Tardive Dyskinesia

Reversibility and Irreversibility of Tardive Dyskinesia following Neuroleptic Withdrawal

being assessed by means of the Abnormal Involuntary Movement Scale (AIMS). In a preliminary evaluation we analyzed the data from the first 16 patients that completed the study (6 male, IO female, age S1.6* 18.6 years). We found a significant improvement in older patients (age> 40 years) on alpha-tocopherol as compared to the placebo group (p < 0.05). No therapeutic effects of alphatocopherol we...

Risperidone Induced Tardive Dyskinesia - a Case Report

Risperidone is a serotonin - dopamine antagonist which has got less propensity to cause tardive dyskinesia than conventional antipsychotics. There have been few reports of tardive dyskinesia induced by risperidone. This is a report of a case of risperidone induced tardive dyskinesia. A 56 year old female with a 6 months history of paranoid schizophrenia, developed bucco-oro-masticatory abnormal...

Treatment of severe neuroleptic-induced tardive torticollis

BACKGROUND: The aim of this paper is to describe a case of severe neuroleptic-induced tardive torticollis successfully treated with a combination of clozapine, clonazepam and botulinum toxin-A. CASE REPORT: The patient, a 30-year old man with a seven-year history of delusional disorder experienced severe right torticollis with painful tightness of the neck and elevation of the shoulder. At this...

Treatment of neurolept-induced tardive dyskinesia

Tardive dyskinesia (TDK) includes orobuccolingual movements and "piano-playing" movements of the limbs. It is a movement disorder of delayed onset that can occur in the setting of neuroleptic treatment as well as in other diseases and following treatment with other drugs. The specific pathophysiology resulting in TDK is still not completely understood but possible mechanisms include postsynapti...